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Experimental drug could thwart measles outbreaks

A new antiviral drug may provide an effective way to treat measles in those who have not been vaccinated.

Mouse model could have predicted drug toxicity that killed 5 in clinical trial

In a 1993 clinical trial of fialuridine--a drug originally designed as a therapy for hepatitis B--5 out of 15 patients died from sudden liver failure. A new study in PLOS Medicine found that mice with humanized livers demonstrate the drug's toxicity.

Improved monitoring of zoonotic diseases could predict future Ebola outbreaks

The ongoing Ebola outbreak in Western Africa underscores the critical need for better global surveillance strategies to combat the emergence of infectious diseases, especially those that have high mortality rates and pose a bioterror threat to countries, according to a new study.

Stabilizing protein complex in brain offers hope for Alzheimer's treatment

A team of investigators has identified a new class of compounds that could work in a specific protein complex in the brain to provide a safe route toward reversing the devastating symptoms of Alzheimer's.

New vaccine could guard against common birth defect-causing virus

An experimental vaccine using a novel defense mechanism could eventually help treat sufferers of a common virus that affects more than half of the U.S. population and causes congenital birth defects in some cases.

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