Scientists use cloning method to create embryonic stem cells
In what is being considered a major advancement in the field of stem cell research, researchers have used a cloning method to successfully reprogram human skins cells into embryonic stem cells.
Top 10 Biotech CEO Pay Packages of 2012
It's a great time to helm a large biotech company, generally. Big biotech players overall posted major growth last year, and their CEOs got richer in the process. Most got fat raises while others saw their bundles of pay pale in comparison to 2011 figures.We surveyed the total compensation packages of the 10 largest biotech companies based on market capitalization as of early May, sleuthing mostly proxy statements for the financial details on pay for some of the most powerful people in the industry.
Last year the chief executives of the 10 companies garnered total compensation of $115.93 million, a 16.57% jump from the $99.45 million in total pay the execs got in 2011.
Biopharma's Top R&D Spenders - 2012
Add up the top-line R&D spending for the top 10 pharma companies in the world and you'd think that nothing had changed from 2011 to 2012. But you'd be very wrong. Big Pharma's heavy hitters in R&D have a wildly mixed record in a fast-changing field.The gross research budgets for these companies hit $70.37 billion last year, down ever so slightly from $70.38 billion the year before, when viewed at constant exchange rates. But while most companies carefully stayed on an unchanged budget track--Novartis ($NVS), Merck ($MRK), J&J ($JNJ), GlaxoSmithKline ($GSK), Sanofi ($SNY), Eli Lilly ($LLY), AstraZeneca ($AZN) and Abbott ($ABT)--Pfizer ($PFE) registered the big drop in spending that had long ago been forecast. Roche ($RHHBY), meanwhile, saw its numbers jump in the face of some big, one-time restructuring costs. And Abbott ($ABT) is making an appearance for the last time as AbbVie ($ABBV) has now spun out to forge its own unique path in the biopharma business. Read the report >>
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Cambridge scientists find molecular catalyst behind Alzheimer's
U.K. researchers may have identified a catalytic trigger for the onset of Alzheimer's disease--a finding that could help doctors diagnose the disease earlier and potentially pave the way for a new class of drugs desperately needed to help treat the debilitating disease.
UPDATED: Lundbeck depression drug improves attention, memory in animal model
Danish pharmaceutical group Lundbeck on Wednesday reported that its investigational depression drug vortioxetine improved a number of cognitive functions in preclinical animal models.
Alnylam reports positive preclinical results for RNAi therapy to treat rare metabolic disease
Alnylam Pharmaceuticals has reported upbeat preclinical findings in a proof-of-concept study for its RNAi therapeutic program to treat porphyria, including acute intermittent porphyria, a rare genetic metabolic disorder caused by an enzyme deficiency.
Drug boosts effectiveness of radiation therapy for brain tumors
An enzyme inhibitor that helps repair DNA damage may provide a new way to boost the effectiveness of radiation therapy for a lethal type of brain cancer.
New agent halts progression of childhood bone cancer in preclinical study
A new drug developed by researchers at Georgetown University Medical Center may be able to stop the progression of a rare bone cancer that affects children and adolescents.
Researchers pinpoint protein involved in cancer cell death
MIT researchers may have discovered a key protein involved in cell death--one that could help kill remaining cancer cells after chemotherapy.
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When studies of AbbVie's chloesterol drug Niaspan raised questions about its effectiveness, analysts suggested it would lose its blockbuster status. But in the face of falling sales, AbbVie's former parent Abbott Laboratories simply raised the price.
The FDA yesterday responded to a Forbes op-ed from Steven Nissen, Chairman of the Department of Cardiovascular Medicine at the Cleveland Clinic, published earlier that day. In it, Nissen railed the...
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