Many drugs used to treat lung, breast and pancreatic cancers also promote drug resistance and can ultimately spur tumor growth. Now, researchers may be able to predict which individual tumors will metastasize and spread when treated with certain drugs.
Academic research institutions play a crucial role in the drug development process, especially on the preclinical research and drug discovery side, as Big Pharma companies are increasingly cutting back their R&D spending. While many of the research institutions featured here are still doing plenty of basic science research, interest seems to be growing among these universities in repurposing existing drugs or those that never made it into the marketplace because of safety issues.
We've taken a look at some of the best research institutions in the U.S. and ranked by them by their level of funding from the National Institutes of Health, the largest funder of biomedical research in the world. The report highlights some of the important drug discovery research coming out of these universities that FierceBiotech Research covered in 2013, but it is by no means a comprehensive look at every research initiative at these institutions.
FierceBiotech is now available on iPhone and iPad!
This is the best FierceBiotech reading experience we've ever created. Swipe right-to-left within articles to quickly scan the latest news. Get breaking news alerts sent to your mobile device so you're the first to know when a major story unfolds. Download it today; the app is an essential complement to our e-mail newsletter and website.
Android users: We're on track to have an app complete by the end of the year.
Have something to say? Join the conversation at
FierceBiotech's LinkedIn group.
POPULAR COMMENT THREADS
Scientists report that they have replicated a method of growing stem cells from adults using cloning techniques--a discovery that could help propel patient-specific regenerative therapies for a myriad of medical conditions and diseases.
Researchers are one step closer to creating a human vaccine for Helicobacter pylori, a bacterium found in 50% of the world's population that infects the stomach and causes chronic gastric inflammation, which can lead to ulcers and stomach cancer.
The Alzheimer's research field has been marked by one failure after another in pursuit of effective treatments, but Cambridge, MA-based NeuroPhage Pharmaceuticals thinks it can tackle the devastating disease with a novel approach.
A new antiviral drug may provide an effective way to treat measles in those who have not been vaccinated.
In a 1993 clinical trial of fialuridine--a drug originally designed as a therapy for hepatitis B--5 out of 15 patients died from sudden liver failure. A new study in PLOS Medicine found that mice with humanized livers demonstrate the drug's toxicity.
The ongoing Ebola outbreak in Western Africa underscores the critical need for better global surveillance strategies to combat the emergence of infectious diseases, especially those that have high mortality rates and pose a bioterror threat to countries, according to a new study.
From Our Sister Sites
Going well beyond the standard sponsor-CRO relationship, Biogen Idec has recruited Quintiles to revamp its clinical development process, giving the contractor a seat at the R&D table to improve trial efficiency.
With a host of biologic products in its pipeline, Bristol-Myers Squibb sees the need for more capacity for making large-molecule drugs and has decided to build on a relationship it already has with South Korea's Samsung BioLogics.