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  • Emory team links inflammation to a third of all cases of depression

    Researchers say that persistent and high inflammation in the brain affects connections relating to important symptoms that are currently difficult to treat, triggering up to a third of all cases of depression. And they believe their discovery can point to other therapeutic remedies for depression

U.K. investigators publish small, promising study of Victoza for NASH

Investigators at the University of Birmingham in the U.K. have published the results of a small but intriguing study that has highlighted the potential of Novo Nordisk's blockbuster diabetes drug Victoza (liraglutide) for NASH, an increasingly common liver disease.

Berkeley lab develops a new nanocarrier that targets glioblastoma

Nanocarriers are microscopic synthetic particles that can deliver therapeutic drugs to a required area in the body. Now researchers say they have developed a new class of nanocarriers, prompting optimism in the long fight against aggressive cases of glioblastoma multiforme.

Arno's HDAC inhibitor looks promising in preclinical cachexia study as cash runs low

Investigators at The Ohio State University Comprehensive Cancer Center say they've nailed down fresh preclinical evidence that an experimental HDAC inhibitor can guard against muscle wasting in cancer cases.

Sanford Burnham team sees promise in new melanoma drug

Scientists at Sanford Burnham Prebys Medical Discovery Institute say that a new molecular machinery-targeting drug dubbed SBI-756 demonstrated preclinical evidence of success in a mouse model for melanoma.

UCSD team targeting new stress pathway in Alzheimer's program

Despite repeated assurances from rival camps that toxic loads of amyloid beta and tau are likely causes of Alzheimer's disease, no one is quite sure what is going on and clinical failures are routine. But investigators at UC San Diego School of Medicine say they have been garnering some preclinical clues that would suggest there could be a new pathway to follow in the clinic.