Topic:

Breakthroughs

Latest Headlines

Latest Headlines

Protein 'map' points way to combating chemo-resistant cancer

In an effort to better understand a certain disease-causing enzyme, British researchers have created a "map" of more than 100 proteins this enzyme is known to affect. They then identified a druglike molecule that blocks this enzyme to preserve these essential proteins.

New technique generates stem cells at highly efficient rate

Scientists at the New York University Langone Medical Center have developed a new technique that uses three familiar compounds, including vitamin C, to generate adult stem cells into pluripotent stem cells at a dramatically more efficient rate--more than 20-fold compared to the current method.

Viral inducers plus antibodies thwart latent HIV in mice

A new strategy that uses broadly neutralizing antibodies combined with a cocktail of viral-inducing compounds may be able to stop HIV from rebounding, according to researchers at Rockefeller University.

Bacteria injection shrinks tumors in animals

A bacteria-based injectable therapy shrunk tumors and completely eradicated others when tested in dogs and rats, according to a new study.

Small molecule inhibitor reverses cognitive deficits of Alzheimer's in mice

Researchers have used a new drug compound to successfully reverse brain deficits caused by Alzheimer's in animal models. The compound, TC-2153, inhibits the negative effects of a protein called striatal-enriched tyrosine phosphatase--a process that scientists found is key to restoring functions in learning and memory.

Glaxo: Ebola vaccine could be ready by 2015

British drugmaker GlaxoSmithKline says it is ready to begin clinical trials on an Ebola vaccine later this year and could have the vaccine available by 2015.

Experimental vaccine for C. difficile successful in animal models

An experimental vaccine for Clostridium difficile provided protection in 100% of mice and monkeys that received it. With antibiotic resistance on the rise, the vaccine could be a valuable preventive measure against the infection, which kills about 30,000 Americans every year.

'Fossil' virus discovery could lead to HIV immunotherapy

A new discovery of an ancestral fossil virus buried within everyone's genomes might provide the key to eradicating HIV.

Genetic variant may protect against Alzheimer's

Drug development in the Alzheimer's field has been riddled with failures, and many research efforts have focused on pinpointing genetic and environmental factors responsible for causing or accelerating the progression of the disease.

Compound prevents blindness, diabetes in rodents

A chemical compound designed by researchers at the University of California, San Francisco, protected mice and rats against degenerative forms of blindness and diabetes by targeting a central stress response area.