Massachusetts Institute of Technology News
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MIT scientists reverse autism, retardation in mice
Researchers from the Picower Institute for Learning and Memory at Massachusetts Institute of Technology have reversed mild retardation and severe autism in mice by inhibiting the enzyme called p21-activated kinase (PAK). Their study focused on Fragile X Syndrome (FXS)--a leading cause of retardation and autism--which is linked to a mutated X chromosome gene. The PAK enzyme controls the connections between neurons and the brain.
"Strikingly, PAK inhibition also restored electrical …
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