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Drug switches on fat-burning gene in mice
Ronald M. Evans, an investigator at The Salk Institute in San Diego, has developed a drug that switches on the PPAR-d gene in mice, protecting them against weight gain from high-calorie and high-fat diets. The drug--which mimics fat--triggers their metabolisms and generates a physical response similar to exercising. After treatment, the mice had lower levels of fatty acids, triglyceride and sugar levels. These mice also exhibited much greater stamina, allowing them to exercise twice as …
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