Scientists identify path to addiction drug therapy

A group of researchers has identified genes that can help a person quit smoking. The study, published in the journal BMC Genetics, brings researchers a step closer toward tailoring individualized drug therapy for addiction based on an individual's unique genetic makeup. The research was conducted by Dr. George Uhl at NIDA's Intramural Research Program and a team led by Dr. Jed Rose at the Center for Nicotine and Smoking Cessation Research at Duke University Medical Center. 

"This research marks the first time we've been able to identify genes involved in the ability to quit smoking," says NIDA Director Dr. Nora D. Volkow. "It marks a movement from identifying the genetics of addiction vulnerability to identifying the genetic basis of successful abstinence. This knowledge could impact the success rate of cessation programs by helping health care providers choose the most appropriate treatment based on individual differences."

- read the release on their work

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