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Mice burn off fat after scientists delete a gene

Deleting the IKKE gene from mice allowed the animals to eat a diet rich in lard without gaining weight. And the researchers say the same approach has the potential to control weight in humans.

"We've studied other genes associated with obesity--we call them 'obesogenes'--but this is the first one we've found that, when deleted, stops the animal from gaining weight," senior study author Alan Saltiel, the Mary Sue Coleman Director of the University of Michigan Life Sciences Institute, said in a university news release.

Eliminating the IKKE gene apparently works by speeding the metabolism of mice, spurring them to burn more calories. "The knockout mice are not exercising any more than the control mice used in the study. They're just burning more energy," Saltiel said. "And in the process, they're generating a little heat, as well--their body temperature actually increases a bit."

- read the story from HealthDay News

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Comments

I have a concern regarding, the extraction of the codone plus one IKKE: Firstly, fat globules are excellent for the body. However, not in extreme amounts. Adipose tissue serves as a cusion and o is, enmeshed in our integumentary system. I believe that fat deposits also make collagen and fibrinogen; which restores cellular structure.
If we continue to state fat is bad for the obese. Then we send the wrong message to the slender citizens. Suppose, all obese citizens can achieve slender sleek bodies after this new alleged treatment.
What happens to his or her sugar level?
What happens to his or her salt levels and electrolyte balance?
Does the client become dehydrated or hyperhydrated and needs other medical attentions, to be implemented?

I guess what I am saying is, we need medications which serve the one, two punch a multitasking medication. For instance, a pill which can reduce the level of pain, assisting reducing constipation, and maintain the intestinal ph. A medication that buffers.

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