Drug delivery vehicles' shape could determine efficacy

A group of researchers at the University of Pennsylvania say that string-like nanoparticles survive longer than spherically shaped nanoparticles, which leads them to believe that the right shape is a key concern in designing new delivery vehicles for drugs. Dennis Discher and colleagues at the University of Pennsylvania say that string-like nanoparticles circulated for up to a week in rodents, significantly longer than the carbon nanotubes that have been studied in depth. Their work appears in the April issue of the journal Nature Nanotechnology.

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