Recent Press Releases

Study: Gene therapy superior to half-matched transplant for 'bubble boy disease'

WASHINGTON - April 13, 2015) - New research published online today in Blood, the Journal of the American Society of Hematology (ASH), reports that children with "bubble boy disease" who...

U-M researchers find protein that may signal more aggressive prostate cancers

ANN ARBOR--University of Michigan researchers have discovered a biomarker that may be a potentially important breakthrough in diagnosing and treating prostate cancer. Biomarkers in the body are...

Researchers identify drug target for ATRA, the first precision cancer therapy

Tarrgeted cancer therapies work by blocking a single oncogenic pathway to halt tumor growth. But because cancerous tumors have the unique ability to activate alternative pathways, they are often...

Restoring cellular energy signals may treat mitochondrial diseases in humans

Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in...

Scientists uncover how molecule protects brain cells in Parkinson's disease model

JUPITER, FL, April 15, 2015 - Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found how a widely known but little-studied enzyme protects brain cells in models of...

Melanoma's 'safe haven' targeted for shut-down

Melanoma's 'safe haven' targeted for shut-down 13 April 2015 MELANOMA cells become drug resistant by using surrounding healthy cells to provide a 'safe haven' from treatment,...

Recruiting the entire immune system to attack cancer

Stimulating both major branches of the immune system halts tumor growth more effectively. The human immune system is poised to spring into action at the first sign of a foreign invader, but it often...

Ancient Herbal Therapy Can Prevent—and Reverse—Cardiac Hypertrophy in Mice

Newswise — A natural compound derived from the bark of the magnolia tree, can protect the heart from hypertrophy, a thickening of cardiac muscle often caused by chronic high blood pressure that...

New target for anticancer drugs: RNA

Some messenger RNAs have unique tags that could be promising drug target Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of...

NIH-funded scientists identify receptor for asthma-associated virus

Receptor gene variant may increase risk of childhood illnesses, asthma Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of...

Defect found in pancreatic cells could lead to new diabetes treatment

Leaky calcium channels in pancreatic beta cells can lead to high blood sugar NEW YORK, NY (April 6, 2015) --A cellular defect that can impair the body's ability to handle high glucose levels and...

Grazoprevir/Elbasvir, Merck's Investigational Chronic Hepatitis C Therapy, Granted FDA Breakthrough Therapy Designations; New Phase 2 and 3 Data in Multiple HCV Patient Types to be Presented at The International Liver CongressTM 2015

Congress Highlights Include Results from Trials in a Wide Range of HCV Patients -- Patients with Chronic Kidney Disease, HIV Co-infection, Cirrhosis, and Prior Treatment Failures Company Remains on...

RG-125 (AZD4076), a microRNA Therapeutic Targeting microRNA-103/107 for the Treatment of NASH in Patients with Type 2 Diabetes/Pre-Diabetes, Selected as Clinical Candidate by AstraZeneca

RG-125 (AZD4076), a microRNA Therapeutic Targeting microRNA-103/107 for the Treatment of NASH in Patients with Type 2 Diabetes/Pre-Diabetes, Selected as Clinical Candidate by AstraZeneca April 7,...

Origin of cancer wasting identified in fruit flies

Origin of cancer wasting identified in fruit flies Cell Press Public Release: 6-Apr-2015 The progressive wasting of muscle and fat tissue throughout the body is one of the most visible and...

Oral drug normalizes blood potassium in 98 percent of kidney patients

High potassium increases risk of fatal cardiac arrhythmias SAN ANTONIO, Texas, U.S.A. (March 30, 2015) -- Patients with chronic kidney disease may be treated with a class of medications called Renin...

Weizmann Institute scientists identify a potential drug molecule that stops cancer cells, but not healthy ones, from getting their 'mail'

To stop cancer: Block its messages The average living cell needs communication skills: It must transmit a constant stream of messages quickly and efficiently from its outer walls to the inner...

Calico Licenses Technology from Acclaimed UCSF Laboratory

March 31, 2015 Calico, a company whose mission is to harness advanced technologies to increase understanding of the biology that controls human lifespan, and UC San Francisco have partnered on an...

Restoring IL-17 may treat skin infections related to chronic alcohol consumption

New research published in the Journal of Leukocyte Biology suggests that increased sensitivity to infection in related to chronic alcohol consumption is due to defective host defense responses and...

ERS and ATS publish statement on the current state and future directions of COPD research

The European Respiratory Society (ERS) and American Thoracic Society (ATS) have published a statement describing the current evidence on the diagnosis, assessment and management of chronic...

Protein may improve liver regeneration

FGF21 boosts regenerative ability in mice carrying human PPARα protein (SACRAMENTO, Calif.) — Researchers at UC Davis have illuminated an important distinction between mice and humans:...