Recent Press Releases

Hacking the programs of cancer stem cells

All tumor cells are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can...

Flashing lights and music turn rats into problem gamblers

Adding flashing lights and music to gambling encourages risky decision-making -- even if you're a rat. In research published today in the Journal of Neuroscience, scientists at UBC discovered...

New findings may enhance PARP inhibitors therapy in breast cancer

Findings from a new study reveal that PARP inhibitors, an emerging class of drugs being studied in cancer clinical trials, may be enhanced by combining them with inhibitors targeting an oncogene...

Gene may be important in autism disorders, other neuropsychiatric syndromes

Scientists have identified a gene that appears to play a significant role in raising a person's risk of having more severe subtypes of autism that co-occur with other genetic diseases, such as...

Making weak TB drugs strong again

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed...

Using Electrical Signals to Train the Heart's Muscle Cells

Columbia Engineering researchers have shown, for the first time, that electrical stimulation of human heart muscle cells (cardiomyocytes) engineered from human stem cells aids their development and...

Rapastinel (GLYX-13) Shown to Improve Ketamine or PCP-Induced Cognitive Impairment in Mice

-Data published in Behavioural Brain Research DUBLIN, Jan. 19, 2016 /PRNewswire/ -- Allergan plc (NYSE: AGN), a leading global pharmaceutical company, announced today that new data on the...

New TSRI study shows path to 'dial down' autoimmunity without compromising immune response

LA JOLLA, CA - Jan. 19, 2016 - A new study led by scientists at The Scripps Research Institute (TSRI) shows how dangerous autoimmune responses, seen in diseases such as lupus and multiple sclerosis,...

Scientists find new gene fault behind ovarian cancer

Women who carry an inherited fault in the gene BRIP1 are over three times more likely to develop ovarian cancer than those without the fault, according to a study published in the Journal of the...

Researchers discover novel factor in Parkinson's disease

PUBLIC RELEASE: 12-JAN-2016 Boston--A team of local researchers have discovered a previously unknown cellular defect in patients with idiopathic Parkinson's disease, and identified a sequence of...

Mayo Clinic researchers reduce stem cell dysfunction and metabolic disease in aged mice

ROCHESTER, Minn. -- Mayo Clinic researchers have taken what they hope will be the first step toward preventing and reversing age-related stem cell dysfunction and metabolic disease. That includes...

Experimental Drugs That Change Energy Supply in Cells Could Slow Brain Tumor Growth

Experimental drugs that alter cell metabolism also halted tumor growth and extended survival in mice with cancers caused by a gene mutated in several types of brain tumors, according to a new study...

TSRI Scientists Find Protein 'Talks' to Wrong Partners in Cystic Fibrosis

LA JOLLA, CA – November 30, 2015 – Scientists at The Scripps Research Institute (TSRI) have found evidence that a mutant protein responsible for most cases of cystic fibrosis is so busy...

Diabetes drug could be used to combat fatty liver disease, research shows

New research published in The Lancet has shown that a drug, currently used in the treatment of Type II diabetes, can be effective in clearing fatty liver disease from some patients. The researchers...

Brushing up peptides boosts their potential as drugs

Peptides promise to be useful drugs, but they're hard to handle. Because peptides, like proteins, are chains of amino acids, our bodies will digest them and excrete the remnants. Even if...

Gene therapy: A promising candidate for cystic fibrosis treatment

An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented...

Protein curbs spread of prostate cancer to bone

Scientists from Lawrence Livermore National Laboratory, in collaboration with researchers from University of California campuses at Merced and Davis, have found that a specific secreted protein...

A drug to encourage the "browning" of white fat to fight obesity

A rose might be a rose, but fat is not always what it seems. White fat cells store a form of fat called triglycerides for energy and contribute to obesity, but brown fat burns triglycerides. Only...

Warp Drive Bio Announces Breakthrough in the Ability to Target the Previously Undruggable Oncogene RAS

New Drug Modality Will Be Deployed Broadly Against Undruggable Targets – Initial Program Targets Multiple Forms of RAS CAMBRIDGE, Mass.--(BUSINESS WIRE)--Warp Drive Bio, a leading biotechnology...

Protein movement of hair bundles in the inner ear may preserve hearing for life

Finding holds promise for repairing damaged hearing Each single hair bundle within the live zebrafish ear contains fascin 2b fused with green fluorescent protein. In this time coarse, the fascin 2b...