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Published on FierceBiotech Research (http://www.fiercebiotechresearch.com)

Transplants offer possible new cure for diabetes

By admin
Created Sep 13 2006 - 8:01pm

Taking precursors of the pancreas of embryonic pigs and transplanting them into rats was an effective way to get them to start producing insulin without triggering a response from the immune system, according to researchers from Washington University School of Medicine in St. Louis. As a result, they were able to cure not only type 1 but type 2 diabetes in the animal models. Their work points to a possible therapy for type 2 diabetes that won't require powerful immune suppressant drugs that are needed to protect transplants.

"Finding that we can cure type 2 diabetes in the same way is very significant because in humans type 2 diabetes is almost 20 times more prevalent than type 1 diabetes," says senior author Marc R. Hammerman, M.D., the Chromalloy Professor of Renal Diseases in Medicine. "There are about 200 million type 2 diabetics worldwide, and the incidence is rapidly increasing."

- read this St. Louis Post-Dispatch article [1] on diabetes research


Source URL:
http://www.fiercebiotechresearch.com/story/transplants-offer-possible-new-cure-for-diabetes/2006-09-14