Using in vitro and animal models, researchers have found that vesicular stomatitis virus--a zoonotic virus in the same family as rabies--kills melanoma cells while leaving noncancerous cells virtually unscathed.
In an ambitious effort to find more personalized treatments for cancer and other complex diseases, Oregon Health & Science University in Portland and Intel are teaming up to develop new computing technologies to map an individual's genetic profile more quickly, precisely and cost-effectively.
Researchers have transformed human embryonic stem cells into nerve cells that helped mice regain the ability to learn and remember, a notable feat in stem cell research that could lead to new models for drug screening and discovery.
Scientists have identified multiple metabolic expression changes associated with cancer as well as hundreds of new potential drug targets that could cut off a tumor's fuel supply or interfere with its ability to produce essential building blocks.
A therapy derived from a weakened version of a deadly kind of bacteria reduced metastasis of pancreatic cancer in mice with no obvious ill effects, according to a new study.
A new mouse model of autism adds to growing evidence that genetics is a strong factor, if not the strongest, driving the neural development disorder.
Scientists think they've found a link between antibody makeup and ethnicity--evidence that that some ethnic groups may be more susceptible to certain diseases or respond to diseases differently than people of other backgrounds.
Antibody technology holds promise for treating a wide array of diseases, and designing new antibodies is a hot area in biotech research right now. One company is developing a new class of antibodies to combat cancer.
High cholesterol is often named as a risk factor for heart disease and stroke, but it may be connected to another disease as well--Alzheimer's.
Scientists at Cleveland's Case Western Reserve School of Medicine have developed a technique in mice that converts skin cells to the kind of brain cells that get damaged in diseases like multiple sclerosis, cerebral palsy and other so-called myelin disorders.
Mersana Therapeutics thinks it's developed the next generation of cancer treatment drugs. Called antibody-drug conjugates (ADCs), Mersana has developed two compounds that connect small molecule anti-cancer drugs and tumor-targeting antibodies in a single package.
For the first time, scientists have genetically engineered a lab rat that has the full range of brain changes associated with Alzheimer's disease--that is, it more accurately mirrors the brain of a person with the disease.
The body's ability to process fats has been connected to certain diseases like Alzheimer's and Parkinson's. Researchers have pinpointed an enzyme--ACOT7--in a mouse model that keeps the fats levels of neurons in the brain in check.
The common sweetener mannitol--already approved by the FDA as an intravenous diuretic--may also harbor properties that could help treat patients with Parkinson's disease.
Agios Pharmaceuticals may be one step closer to finding a breakthrough approach to treat cancer in a more personalized fashion.
Researchers at Merck are developing a class of new drugs that could help improve treatment options for patients with certain cancers driven by genetic mutations.
In the latest effort to find less harmful treatments for cancer, a researcher at the University of Missouri has developed a new form of radiation therapy that put cancer in remission in mice.
President Barack Obama's highly anticipated BRAIN initiative--short for Brain Research Through Advancing Innovative Neurotechnologies--has the lofty goal of mapping the human brain in hopes of finding new treatments for diseases like Alzheimer's, Parkinson's and other neurological disorders.
A study conducted in rats suggests that stimulating a part of the brain called the prefrontal cortex--which essentially acts as an on/off switch--could help treat addiction problems in people.
A new therapeutic may be more effective against a variety of cancers--including colon, head and neck, mesothelioma, ovarian and pancreatic cancers--than previously thought.