Inovio vaccine kills malaria, boosts immune response in animals

A malaria shot designed by vaccine maker Inovio Pharmaceuticals killed the disease in infected cells in animals while boosting immune responses, according to a new study.

Pluristem's stem cell therapy improves tendon injuries in rats

In rats with tendon injuries that were treated with Pluristem Therapeutics' PLacental eXpanded (PLX) stem cell therapy, animals showed tendon healing at two and four weeks following injection, compared to saline-treated rats, according to the Haifa, Israel-based company.

Seattle BioMed wins $16M NIH grant for TB research

Seattle BioMed has been awarded a $16.6 million grant from the National Institute of Allergy and Infectious Diseases that will allow it to perform what it believes will be the most comprehensive analysis to date of tuberculosis progression from latent infection to active disease.

U.K. nonprofits offering funding for novel Parkinson's targets

The U.K. technology transfer organization MRC Technology and the nonprofit Parkinson's UK are partnering in the search for new therapeutic targets to slow, stop or reverse the progression of Parkinson's diseases.

Gene repair technique could have various therapeutic uses

Scientists may have unlocked a way to therapeutically correct genetic defects by using a new technique that targets and repairs defective genes.

Stem cell combo therapy extends survival of mice with brain tumors

A new stem cell treatment that combines neural stem cells with chemo-radiotherapy drugs could provide a better way to combat glioblastoma, the most common and lethal form of adult brain cancer.

Newly discovered proteins could play role in destroying cancer cells

U.K. researchers have discovered what role a newly identified team of proteins play in the process of cell division, and they say that harnessing these proteins could provide a new way to kill cancerous cells.

NIH to open genomic data of HeLa cells to researchers

Biomedical researchers will now be able to apply for access to the whole genome data of an important cell line known as HeLa.

University of Maryland, Baltimore partners with 5 biotech companies

The University of Maryland, Baltimore, has forged new agreements with 5 life sciences companies in the Baltimore-Washington metropolitan region through its commercialization arm, University of Maryland Ventures.

Opioid receptor research could help shape drug development for addiction

Investigators from the Florida campus of the Scripps Research Institute have found that a compound that favors a certain biological pathway could provide scientists with a roadmap for future development of more effective drugs for addiction.

New hep C model could pave way for novel treatments

Scientists may soon be able to find novel ways to treat hepatitis C using a new laboratory model developed by researchers at the Icahn School of Medicine at Mount Sinai in New York.

NIH team sees diabetes drug as a possible tool for extending life

A drug used since the 1960s to treat Type 2 diabetes appears to prolong both life and good health in middle-aged male mice. If further research supports the early results, the discovery could allow doctors to use the drug to stave off metabolic decline in humans as they grow older.

Plant-based inhibitor could halt HIV infection

A compound derived from soybeans and other plants may have HIV-fighting properties, according to new research by scientists at George Mason University.

New compound kills resistant prostate cancer cells

A team at the La Jolla, CA-based Sanford-Burnham Medical Research Institute has developed a compound called SMIP004 that causes a decrease in the number of androgen receptors--proteins located in prostate cancer cells that are activated by testosterone.

La Jolla, Kyowa Hakko Kirin partner on autoimmune disease drug discovery

La Jolla Institute for Allergy and Immunology and Kyowa Hakko Kirin California, a subsidiary of Japanese pharmaceutical company Kyowa Hakko Kirin, have signed a 6-year drug discovery pact to develop therapies for a wide range of autoimmune diseases.

New drug target found for asthma

Targeting a key enzyme associated with heart disease could offer a new way to treat asthma, which affects billions of people worldwide, including 8.5% of the U.S. population.

UCLA team IDs anti-amyloid compounds to treat brain diseases

A team of scientists is for the first time using a structure-based drug design approach to find new compounds designed to treat neurodegenerative disorders like Alzheimer's, Parkinson's and Lou Gehrig's diseases.

Novavax joins H7N9 vaccine race, reports positive preclinical data

The latest outbreak of avian influenza in China earlier this year has spurred drug development interest in a vaccine to combat the deadly H7N9 strain, which health officials around the world have said has the potential to become a pandemic.

Antibody effective at fighting norovirus in chimps

A monoclonal antibody developed by researchers at the National Institute of Allergy and Infectious Diseases could lay the groundwork for effective therapies against norovirus, which has in recent years infected school campuses, cruise ships, hospitals and nursing homes.

Inovio DNA cancer vaccine causes tumor death in animals

A DNA cancer vaccine developed by Blue Bell, PA-based Inovio Pharmaceuticals caused tumor cell death and increased the rate of survival in animal studies.