NIH faces flat funds in president's 2015 budget proposal

Announced earlier this week, President Barack Obama's proposed budget for 2015 includes $30.4 billion for the National Institutes of Health, a slight increase of $211 million over this fiscal year's budget.

OHSU opens new stem cell research center

Oregon Health & Science University is opening a new Center for Embryonic Cell and Gene Therapy to study experimental treatments for Parkinson's disease, multiple sclerosis and a range of other conditions caused by diseased or injured cells in the human body.

Stem cell therapy improves Parkinson's symptoms in monkeys

International Stem Cell Corp. is inching closer to bringing its stem cell therapy for Parkinson's to the FDA in hopes of eventually reversing the disease's symptoms in people.

HIV immune discovery could lay the groundwork for a vaccine

A new discovery that explains how the body's immune system makes a potent antibody that blocks HIV infection may be an important step toward developing a vaccine against the virus.

New anti-inflammatory molecule could provide a model for new drug design

Researchers think they've discovered why previous efforts at targeting the enzyme LTA4 hydrolase, a key player in the body's inflammatory response, have failed and produced a new molecule that may prove more successful.

BioCryst compound prevents Marburg virus in monkeys

An experimental antiviral compound developed by BioCryst Pharmaceuticals and the U.S. Army Medical Research Institute of Infectious Diseases provided complete protection in monkeys against Marburg virus and Ebola, two highly virulent pathogens with no effective treatments.

Experimental supplement extends lifespan, stops metabolic disease in mice

A supplement that activates a protein involved in metabolic balance showed an extension in lifespan and improvement in the overall health of mice, according to a new study.

Brain cell communication plays role in regulating Alzheimer's protein

Increased brain cell activity seems to boost levels of the protein tau, a hallmark of Alzheimer's disease, according to researchers. The link could help advance efforts to treat Alzheimer's disease and other neurodegenerative disorders.

NIH makes new database on age-related diseases available to researchers

The NIH has added a huge amount of medical data--from a diverse group of more than 78,000 people with an average age of 63--to Genetic Epidemiology Research on Aging, one of the nation's largest and most diverse genomics projects.

DOD selects Bavarian Nordic to develop vaccine against biological threats

The Department of Defense has selected Denmark's Bavarian Nordic to develop a vaccine against two potential biological pathogens deemed to be threats to national security.

HPV-like vaccine guards against skin tumors in mice

A new vaccine developed by German researchers may be effective against a certain type of skin cancer in organ transplant patients caused by papillomavirus.

Reprogrammed skin cells could provide a way to regenerate liver tissue

Researchers have found a way to transform skin cells into fully functioning mature liver cells that grow on their own after being transplanted into mice.

Global tuberculosis R&D takes hit with AstraZeneca site closure

Last month AstraZeneca said it is shuttering an Indian research site as it moves away from neglected diseases to focus on areas with more potential for growth. The move is a hit to global tuberculosis R&D, which received $10 million from AstraZeneca in 2012.

Scientist: Let's not discredit acid-bath stem cell studies--yet

Some say the recent allegations about a potential stem cell breakthrough unveiled in January by a major Japanese research institution represent a larger problem of irreproducibility in early science research. But others, like Edward Ahn, managing director and chief science officer of Cambridge, MA-based MedCap Advisors, think we shouldn't jump to conclusions quite yet.

Berg, Parkinson's Institute partner to find biomarkers

The Sunnyvale, CA-based Parkinson's Institute and Clinical Center and pharma company Berg are partnering to identify potential biomarkers to help diagnose and treat Parkinson's disease.

Gene therapy regenerates damaged tissue in pigs after heart attack

An experimental gene therapy developed by investigators at the Icahn School of Medicine at Mount Sinai successfully regenerated heart muscle in pigs following a heart attack.

Stem cell switch in neural cells could help treat neurological disorders

A protein previously known for other functions has also been found to act as a switch that decides whether an immature neural cell stays in a stem cell-like state or differentiates into a functional neuron.

Role of adaptor protein could point the way for new diabetes, cancer treatments

A protein known to be part of a complex communications network within the cell has also been found to be associated with important processes involved in cancer and diabetes.

Compound protects mice from Parkinson's-like motor loss

In the Journal of Medicinal Chemistry, scientists report that they've found a new compound that may offer protection against Parkinson's disease.

BioLineRx shows effectiveness of leukemia drug in preclinical study

Israel's BioLineRx has unveiled positive preclinical data for its experimental treatment for chronic myeloid leukemia, a progressive blood and bone marrow cancer.