News

Gene therapy in mice improves Rett syndrome

Scientists have used a gene therapy technique to reverse symptoms of Rett syndrome in mice, showing the potential for clinical application. Rett syndrome, an X-linked autism disorder that primarily occurs in girls, affects one in about 10,000 children a year.

Sodium 'switch' could provide target to treat brain disorders

Researchers at McGill University in Montreal, Canada, have found that sodium acts as a switch for a major neurotransmitter receptor in the brain, known as the kainate receptor.

Study finds new genetic variants linked to blood cancer

Multiple myeloma, one of the most common types of blood cancer, has been linked to a gene that's responsible for regulating the aging process in the human body.

Industry-academic partnerships could help propel metabolic disease research

These alliances benefit not only pharma companies, which gain access to world-class scientists and robust drug discovery programs, but also academic institutions, which increasingly are realizing that relationships with Big Pharma are more and more vital.

Diabetes progression slowed in mice

Chronic inflammation has long been thought to have ties to Type 2 diabetes, and now researchers at the National Institutes of Health believe they have discovered what that connection may be. The findings also point to a possible molecular target for treating the disease, which is a growing epidemic in the U.S.

Nerve cell death reversed in Parkinson's cells

A common ingredient used to fight wrinkles may also have the ability to fight Parkinson's disease. In laboratory tests, researchers found that the chemical, called kinetin, thwarted the death of nerve cells damaged by mutations that cause a hereditary form of Parkinson's.

Inovio vaccine kills malaria, boosts immune response in animals

A malaria shot designed by vaccine maker Inovio Pharmaceuticals killed the disease in infected cells in animals while boosting immune responses, according to a new study.

Pluristem's stem cell therapy improves tendon injuries in rats

In rats with tendon injuries that were treated with Pluristem Therapeutics' PLacental eXpanded (PLX) stem cell therapy, animals showed tendon healing at two and four weeks following injection, compared to saline-treated rats, according to the Haifa, Israel-based company.

Seattle BioMed wins $16M NIH grant for TB research

Seattle BioMed has been awarded a $16.6 million grant from the National Institute of Allergy and Infectious Diseases that will allow it to perform what it believes will be the most comprehensive analysis to date of tuberculosis progression from latent infection to active disease.

U.K. nonprofits offering funding for novel Parkinson's targets

The U.K. technology transfer organization MRC Technology and the nonprofit Parkinson's UK are partnering in the search for new therapeutic targets to slow, stop or reverse the progression of Parkinson's diseases.

Gene repair technique could have various therapeutic uses

Scientists may have unlocked a way to therapeutically correct genetic defects by using a new technique that targets and repairs defective genes.

Stem cell combo therapy extends survival of mice with brain tumors

A new stem cell treatment that combines neural stem cells with chemo-radiotherapy drugs could provide a better way to combat glioblastoma, the most common and lethal form of adult brain cancer.

Newly discovered proteins could play role in destroying cancer cells

U.K. researchers have discovered what role a newly identified team of proteins play in the process of cell division, and they say that harnessing these proteins could provide a new way to kill cancerous cells.

NIH to open genomic data of HeLa cells to researchers

Biomedical researchers will now be able to apply for access to the whole genome data of an important cell line known as HeLa.

University of Maryland, Baltimore partners with 5 biotech companies

The University of Maryland, Baltimore, has forged new agreements with 5 life sciences companies in the Baltimore-Washington metropolitan region through its commercialization arm, University of Maryland Ventures.

Opioid receptor research could help shape drug development for addiction

Investigators from the Florida campus of the Scripps Research Institute have found that a compound that favors a certain biological pathway could provide scientists with a roadmap for future development of more effective drugs for addiction.

New hep C model could pave way for novel treatments

Scientists may soon be able to find novel ways to treat hepatitis C using a new laboratory model developed by researchers at the Icahn School of Medicine at Mount Sinai in New York.

NIH team sees diabetes drug as a possible tool for extending life

A drug used since the 1960s to treat Type 2 diabetes appears to prolong both life and good health in middle-aged male mice. If further research supports the early results, the discovery could allow doctors to use the drug to stave off metabolic decline in humans as they grow older.

Plant-based inhibitor could halt HIV infection

A compound derived from soybeans and other plants may have HIV-fighting properties, according to new research by scientists at George Mason University.

New compound kills resistant prostate cancer cells

A team at the La Jolla, CA-based Sanford-Burnham Medical Research Institute has developed a compound called SMIP004 that causes a decrease in the number of androgen receptors--proteins located in prostate cancer cells that are activated by testosterone.