News

Sangamo's gene editing tech fixes immune flaw in stem cell study

Researchers from Italy's San Raffaele Telethon Institute for Gene Therapy and Sangamo BioSciences have used a gene editing technique to correct a genetic defect in stem cells from an individual with X-linked severe combined immunodeficiency.

GlaxoSmithKline to head tuberculosis drug discovery initiative

As rates of drug-resistant tuberculosis rise across the globe, GlaxoSmithKline is partnering with Switzerland's BioVersys and France's University of Lille to develop a preclinical candidate against the airborne disease.

Pain receptor could be key to longevity, better health in old age

Blocking a pain receptor in humans could help improve lifespan and metabolic health, according to researchers from the University of California, Berkeley.

Preventing biofilm formation could help fight antibiotic resistance

In a discovery that could lead to the development of new antibiotics, investigators from the University of British Columbia have found a new type of antimicrobial molecule that prevents bacteria from forming into biofilms, a frequent cause of infections.

Antisense compound may provide new Alzheimer's treatment

A new antisense compound developed by Saint Louis University scientists restored learning, memory and other behaviors in mice genetically engineered to have Alzheimer's disease.

Neurotrope, Stanford partner to treat neurological disorders with bryostatins

Stanford University is partnering with Plantation, FL-based Neurotrope to study a class of compounds called bryostatins with the aim of developing potential clinical candidates for the treatment of various neurological disorders.

Database IDs new uses for existing drugs

Researchers at the University of Colorado have developed a new database and pattern-matching algorithm that allows drug developers to evaluate drugs and drug combinations for purposes other than their FDA-approved use.

Antigen discovery could advance malaria vaccine

In a discovery that could put a vaccine for malaria closer in sight, scientists have linked a protein to an essential function in malaria-causing parasites that enables them to escape from inside red blood cells and infect the rest of the body.

Nanocarriers that harness fungus traits could deliver drugs to brain

Investigators have designed silicon nanoparticles that could be capable of penetrating the blood-brain barrier. The scientists presented their findings during a symposium at the American Society for Microbiology annual meeting on May 17.

CDC scientist: MERS doesn't present pandemic risk, but other diseases might

Despite its high mortality rate and alarming spread since it was first detected in Saudi Arabia in 2012, a U.S. health official says it's unlikely that Middle East Respiratory Syndrome coronavirus will turn into a pandemic.

Animal model that mimics hep B, C in humans could spur new treatments

To help design next-generation drugs for hepatitis B and C, researchers have developed a humanized mouse model that contains human liver cells and mimics the immune system of people.

Anti-MERS therapies ID'd among existing drugs

Scientists have identified existing drugs and experimental compounds under development that may be able to treat the respiratory illness, which causes pneumonia-like symptoms, such as fever, cough and shortness of breath.

Natural antibacterial clay could fight MRSA, other infections

Researchers from Arizona State University believe that topical clays may be able to thwart MRSA and other bacterial infections while healing skin, providing a natural supplement to currently available antibiotics.

NIH addresses sex bias in preclinical research

NIH will be enacting new guidelines to offset sex bias in the lab, including requiring that grant recipients report the sex of animals and cells used in preclinical studies.

Investigational treatment may provide relief for asthma

Researchers have discovered a novel molecule that prevents T-cells from triggering asthma brought on by allergens, a finding that could treat the nearly 25 million Americans that suffer from the chronic disease.

Naturally occurring molecule could treat Type 2 diabetes

A naturally occurring molecule that mimics some of the effects of physical exercise could be used to treat insulin resistance and Type 2 diabetes, according to Canadian researchers.

Study: Heart attack stem cell treatment may offer little benefit

Despite the promise that stem cell technology has shown for regenerative medicine, heart attack patients who receive an injection of stem cells to regenerate damaged heart tissue may not actually benefit from the therapy.

Biochips, bioprinting offer alternative drug testing options

New technology like organs-on-chips and bioprinted tissues have the potential to test the safety of drugs more accurately and cost-efficiently for a myriad of diseases. FierceBiotech Research highlights some organizations that are working on alternative drug testing technology.

FDA-approved genital warts drug could treat MERS

An injectable drug that's FDA-approved for another use may provide a treatment option for the deadly Middle East respiratory syndrome coronavirus, or MERS, which has killed more than one-quarter of its victims since it first broke out in Saudi Arabia.

Harvard's heart disease-on-a-chip mimics real tissue and disease

Harvard scientists have combined their organ-on-a-chip technology with stem cells to produce functioning human heart tissue carrying an inherited cardiovascular disease, with the aim of creating a more personalized therapy regimen for individual patients.