Vitamin B-3, or niacin, is an essential human nutrient that has been used for more than 50 years to boost levels of HDL, or good cholesterol, in the blood. Now, new research suggests that a form of the vitamin might also be used to treat adult-onset mitochondrial muscle diseases.
The University of California, San Francisco, is teaming up with Japanese drugmaker Daiichi Sankyo for a drug-discovery pact focused on tackling neurodegenerative diseases.
The Lieber Institute for Brain Development is partnering with Astellas, Eli Lilly, Lundbeck, Pfizer and Roche to launch an early-stage research consortium to study the genetic mechanisms at work in brain disorders.
An investigative committee at a leading Japanese research organization has concluded that papers detailing a potential breakthrough in creating embryonic-like stem cells contain falsification and fabrication.
Schizophrenia remains a difficult disease to treat, and Johns Hopkins researchers are studying an experimental anticancer compound that may eventually provide relief to patients by reversing symptoms of the devastating mental disorder.
The discovery of a molecule that coaxes cells to self-destruct may provide a novel way to treat immune disorders and inflammation, according to a new study.
NIH has completed construction of the second phase of its newest building, the John Edward Porter Neuroscience Research Center, at its campus in Bethesda, MD.
In the midst of flat funding for many federal programs as well as last year's across-the-board spending cuts known as sequestration, global health advocacy groups say Congress needs to adopt a long-term budget solution to sustain R&D activities for new drugs, vaccines and other health technologies to combat global health threats.
An antioxidant discovered more than a dozen years ago may be able to treat patients with amyotrophic lateral sclerosis, a devastating neurodegenerative disease that is usually fatal within 5 years of diagnosis that currently has no cure.
Investigators have identified a gene that appears to play a leading role in coordinating the immune system and metabolism, a finding that could have implications for treating Type 2 diabetes and obesity.
In another step toward using stem cells for regenerative medicine, investigators from the University of Wisconsin-Madison have discovered a new way to make skeletal muscle cells and muscle progenitors in bulk from human pluripotent stem cells.
A drug developed by Amylin Pharmaceuticals to treat diabetes may also have Alzheimer's-fighting properties, according to a new study.
Low doses of a well-known class of drugs currently used in much higher doses to treat anxiety and epileptic seizures may be able to treat symptoms of autism, according to new research.
A compound derived from mushrooms may provide a new therapeutic avenue for treating human papillomavirus and curbing HPV-related cancers.
The Japanese Global Health Innovative Technology Fund said it will invest nearly $15 million to advance new drugs for neglected tropical diseases as well as fund the development of a vaccine candidate for tuberculosis.
Researchers have identified two new chemical compounds that preserve leukemic stem cells in culture when these are grown outside the body--a major step toward developing new therapies for leukemia.
Scientists may have cracked the mystery of the origin of the H7N9 avian influenza, which has caused more than 375 infections and 100 deaths. A new study has found that quail and chickens are the likely sources of transmission of H7N9 influenza virus to humans.
A tiny protein found in cone snail venom could provide the foundation for a new class of drugs to treat chronic nerve pain, according to scientists.
Knocking out a certain gene or reducing its expression by using an enzyme inhibitor may provide a new avenue for treating Alzheimer's disease.
Years of flat funding from the National Institutes of Health plus across-the-board federal spending cuts known as sequestration could have deleterious effects for cancer research, says a new study by the American Association for Cancer Research.